| dc.description.abstract | Diabetes mellitus was a disease with macro and micro risk of angiopathy,
which includes the impact of causing cataracts. Diabetic patients with high
sugar levels have a greater chance of developing cataracts at a younger age
and certain tendencies towards cataract type. The aim of the study was to
analyze the correlation between diabetes blood sugar levels and cataract type.
The research design was correlation analysis with Cross-Sectional approach.
Samples in the study were some cataract patients who had a history of diabetes
mellitus in Surabaya Undaan Eye Hospital as many as 125 people, it was taken
using consecutive sampling technique, and fulfilling the criteria of the study
(age range 45 - 65 years, have complete medical records related to the
continuity of sugar examination results in blood, the incidence of cataracts is
not caused by congenital cataracts, juveniles, due to trauma, chemical
exposure to UV radiation). Independent variable was the blood sugar level of
Diabetes mellitus and the Dependent variable was cataract type. The
instruments used were laboratory tests related to blood sugar levels, and
medical diagnosis related to cataract type. Data were analyzed by Spearman
rho, with a significant value <0.05. The results showed a close association
between diabetes and cataracts, where as many as 47.2% with high blood sugar
levels, 40% with nuclear cataract type and from 59 respondents with high
blood sugar levels 26 people experienced nuclear cataract type, with rho value
= 0.001. The mechanism of glucose toxicity in Diabetes Mellitus which causes
cataracts can go through three paths: increased activity of the aldose reductase
enzyme which causes the formation of sugar alcohol, sorbitol and galactitol in
crystalline lenses; through the non-enzymatic replication process; and at high
blood glucose levels a glucose oxidation process will occur which causes
oxidative stress conditions. Maintenance of managing blood sugar levels must
be a concern for diabetics. | en_US |
