DECREASING NAUSEA AND VOMITING DUE TO CHEMOTHERAPY INDUCTION THROUGH PEPPERMINT AROMATHERAPY
Abstract
Nausea and vomiting often appear with under various conditions, including
being a common side effect of using anti-neoplastic drugs. Chemotherapyinduced nausea and vomiting (CINV) was a major problem that can often alter
the quality of life (QoL) and patient adherence to treatment if left untreated.
Aromatherapy peppermint is one form of improvised nonpharmacological
handling of CINV. This study aims to determine the effectiveness of giving
peppermint aromatherapy in reducing CINV. This study was a queasy
experiment with Control Group design, with total sample groups of 285
respondents with consecutive technique. Parameters in this study used Rhodes
Index Nausea Vomiting and Reaching (RINVR). The data were analyzed using
Wilcoxon sign rank test as a test of change of nausea scale of pre and post
vomiting in experimental and control group. The results of the differences
between both groups were tested with Mann Whitney-u test. Wilcoxon sign
rank test analysis, showing differences in the incidence of nausea and vomiting.
The result of a change of decrease in experimental group value ρ = 0,001 is
more significant than the control group with value ρ = 0,020. The difference is
tested with Mann Whitney-u test with the result value ρ = 0.002. Aromatherapy
works in one’s body by triggering the release of neurotransmitter like
enkephalin and endorphin which have an analgesic effect and increase the
feeling of comfort and relax. Through inhalation, the fragrance of aromatherapy
is transmitted through the limbic system into hypothalamus until pituitary and
through the olfactory cortex, into thalamus and then head to the neocortex