Abstract:
Chronic kidney disease (CKD) is a long-term disease where the kidneys have
decreased function. In women who experience prolonged CKD, other problems will
arise, namely Menstrual abnormalities. CKD patients who have just undergone
hemodialysis therapy are prone to stress, if not treated immediately it will disrupt the
menstrual cycle. This research design uses correlation analytic with cross sectional
approach. The population in this study were 49 women who suffered from CKD in the
hemodialysis unit of RSUD Prof. Dr. Soekandar. Sampling using non-probability
sampling technique Consecutive sampling type within a period of 3 weeks. The
sample in this study amounted to 43 people. The instruments used in this research are
DASS questionnaire and Menstrual abnormalities checklist sheet. Data analysis using
logistic regression test. The results showed that 20 respondents (46.51%) had CKD >4
years. For stress levels, it was found that 17 respondents (39.53%) were at mild stress
levels. And 39 respondents (90.70%) experienced Menstrual abnormalities. The
results of the logistic regression test showed that the p-value = 0.048. It can be
concluded that there is a long-standing relationship between chronic kidney disease
and stress with menstrual abnormalities in the hemodialysis unit of RSUD Prof. Dr.
Soekandar. Women who suffer from CKD in their bodies will experience
hyperprolactinemia which will disrupt the menstrual cycle. A person who has just been
diagnosed with CKD is prone to stress, which stress will stimulate the release of
Corticotropic Releasing Hormone (CRH). Hyperprolactinemia and CRH can affect the
performance of Gonadotropin-releasing hormone (GnRH) which lead to menstrual
abnormalities
