THE RELATION OF LONG SUFFERING CHRONIC KIDNEY DISEASE (CKD) AND STRESS WITH MENSTRUAL ABNORMALITIES IN HEMODIALYSIS UNIT RSUD PROF. DR. SOEKANDAR

Abstract

Chronic kidney disease (CKD) is a long-term disease where the kidneys have decreased function. In women who experience prolonged CKD, other problems will arise, namely Menstrual abnormalities. CKD patients who have just undergone hemodialysis therapy are prone to stress, if not treated immediately it will disrupt the menstrual cycle. This research design uses correlation analytic with cross sectional approach. The population in this study were 49 women who suffered from CKD in the hemodialysis unit of RSUD Prof. Dr. Soekandar. Sampling using non-probability sampling technique Consecutive sampling type within a period of 3 weeks. The sample in this study amounted to 43 people. The instruments used in this research are DASS questionnaire and Menstrual abnormalities checklist sheet. Data analysis using logistic regression test. The results showed that 20 respondents (46.51%) had CKD >4 years. For stress levels, it was found that 17 respondents (39.53%) were at mild stress levels. And 39 respondents (90.70%) experienced Menstrual abnormalities. The results of the logistic regression test showed that the p-value = 0.048. It can be concluded that there is a long-standing relationship between chronic kidney disease and stress with menstrual abnormalities in the hemodialysis unit of RSUD Prof. Dr. Soekandar. Women who suffer from CKD in their bodies will experience hyperprolactinemia which will disrupt the menstrual cycle. A person who has just been diagnosed with CKD is prone to stress, which stress will stimulate the release of Corticotropic Releasing Hormone (CRH). Hyperprolactinemia and CRH can affect the performance of Gonadotropin-releasing hormone (GnRH) which lead to menstrual abnormalities